Febuxostat is a potent, non-purine selective inhibitor of xanthine oxidase used for the chronic management of hyperuricaemia in patients with gout. It is often prescribed as an alternative for patients who cannot tolerate allopurinol or in whom allopurinol has proven ineffective.

Allopurinol is a widely used urate-lowering medication primarily indicated for the long-term management of gout and the prevention of uric acid kidney stones. It is highly effective in reducing elevated blood uric acid levels (hyperuricaemia) to prevent recurrent gout attacks.