Linagliptin is a DPP-4 inhibitor that helps lower blood sugar levels in adults with type 2 diabetes. Unlike many other diabetes medications, it is primarily excreted through the bile and gut, making it suitable for patients with kidney problems without needing dose adjustments.

Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor used to manage type 2 diabetes. It works by increasing the levels of natural substances called incretins, which help to control blood sugar by increasing insulin release and decreasing glucagon levels.