Dapagliflozin is an SGLT2 inhibitor used to treat type 2 diabetes, heart failure, and chronic kidney disease. It lowers blood sugar by causing the kidneys to excrete excess glucose in the urine and offers significant protective effects for the heart and kidneys.

Losartan is an angiotensin II receptor blocker (ARB) primarily used to treat high blood pressure and protect the kidneys in diabetic patients.