Levofloxacin is a potent, broad-spectrum fluoroquinolone antibiotic. It is highly effective against a wide array of both Gram-positive and Gram-negative bacteria. Due to its strength and potential for serious side effects, it is typically reserved for treating severe, complicated, or difficult-to-treat infections, such as severe pneumonia, acute bacterial exacerbation of chronic bronchitis, and complicated urinary tract infections, when alternative treatments are ineffective.