Etoricoxib is a highly selective COX-2 inhibitor, a specialised class of nonsteroidal anti-inflammatory drugs (NSAIDs). It is renowned for providing potent and rapid relief from pain and inflammation. It is frequently prescribed for managing chronic joint conditions such as osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and for the acute treatment of severe gout attacks.

Celecoxib is a selective COX-2 inhibitor, representing a specialised class of nonsteroidal anti-inflammatory drugs (NSAIDs). It was developed to provide robust pain and inflammation relief while significantly minimising the gastrointestinal toxicity associated with traditional non-selective NSAIDs.