Prochlorperazine is a phenothiazine antiemetic and antipsychotic medication used to treat severe nausea and vomiting, as well as conditions like vertigo and schizophrenia.

Domperidone is a dopamine antagonist with antiemetic properties, primarily used to relieve nausea and vomiting. Unlike some other antiemetics, it does not readily cross the blood-brain barrier, reducing the risk of central nervous system side effects.

Metoclopramide is a prokinetic agent and antiemetic used to treat nausea, vomiting, and delayed stomach emptying (gastroparesis). It helps speed up the movement of food through the stomach and intestines.